James Mitchell, PhD

Assistant Professor at the University of Colorado Anschutz. Focusing on Human-Computer Interaction, Clinical Decision Support, and Artificial Intelligence.

Dr. James Mitchell

About Me

I am an Assistant Professor in the Department of Biomedical Informatics at the University of Colorado Anschutz. My research sits at the intersection of human-computer interaction, clinical decision support, and artificial intelligence, designing user-centred systems that improve how clinicians access and act on information at the point of care.

I completed my PhD at Keele University, working in partnership with University Hospital North Midlands NHS Trust as part of a funded project to develop bedside mobile clinical guidelines.

Current projects include LLM-based feedback systems for clinical environments, privacy-preserving NLP for clinical acronym disambiguation, drug-drug interaction decision support, and wearable-based anxiety detection. I collaborate with Stanford, University of Utah, Vanderbilt, Keele University, and more.

Research Projects

ClarifAI

An LLM-based system for collecting structured AI feedback in hard-to-reach clinical environments, enabling continuous improvement of decision-support tools at the point of care.

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PLACID

A privacy-preserving LLM framework for inferring and disambiguating clinical acronyms at scale, improving EHR readability and reducing documentation ambiguity.

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Bedside Clinical Guidelines

A user-centred mobile application delivering evidence-based clinical guidelines at the point of care, developed in close collaboration with University Hospital North Midlands NHS Trust.

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Selected Publications

PLACID: Privacy-preserving Large language models for Acronym Clinical Inference and Disambiguation

Aithal, Kotz & Mitchell (2026), arXiv; accepted poster, AMIA Symposium 2026

Large Language Models Clinical NLP
arXiv:2603.23678

Navigating Complexity: Enhancing Pediatric Diagnostics With Large Language Models

Mitchell & Bennett (2024), Pediatric Critical Care Medicine, 25(6):577–580

Large Language Models Pediatric Care
DOI Link

A Rapid Review on Current and Potential Uses of Large Language Models in Nursing

Hobensack et al. (2024), International Journal of Nursing Studies, 154, 104753

Large Language Models Nursing Informatics
DOI Link

Artificial Intelligence-Based Technologies in Nursing: A Scoping Literature Review of the Evidence

von Gerich et al. (2022), International Journal of Nursing Studies

AI in Nursing Literature Review
DOI Link